CRSP6 monoclonal antibody (M01), clone 4D4
产品名称： CRSP6 monoclonal antibody (M01), clone 4D4
英文名称： CRSP6 monoclonal antibody (M01), clone 4D4
产品编号： H00009440-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CRSP6.
- Immunogen:
- CRSP6 (AAH21101, 551 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- FSNHVGLGPIESIGNASAITVASPSGDYAISVRNGPESGSKIMVQFPRNQCKDLPKSDVLQDNKWSHLRGPFKEVQWNKMEGRNFVYKMELLMSALSPCLL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Identification of target genes for the CDK subunits of the Mediator complex.
Tsutsui T, Fukasawa R, Tanaka A, Hirose Y, Ohkuma Y.Genes Cells. 2011 Nov 27. doi: 10.1111/ j.1365-2443. 2011.01565.x.
- Applications
- Western Blot (Cell lysate)
- CRSP6 monoclonal antibody (M01), clone 4D4 Western Blot analysis of CRSP6 expression in Hela NE ( Cat # L013V3 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to CRSP6 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.2 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to CRSP6 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CRSP6 is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 9440
- GeneBank Accession#:
- BC021101
- Protein Accession#:
- AAH21101
- Gene Name:
- MED17
- Gene Alias:
- CRSP6,CRSP77,DRIP80,FLJ10812,TRAP80
- Gene Description:
- mediator complex subunit 17
- Omim ID:
- 603810
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq
- Other Designations:
- cofactor required for Sp1 transcriptional activation, subunit 6 (77kD),cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa,thyroid hormone receptor-associated protein, 80-KD subunit,vitamin D receptor interacting protein 80-kD